Contact Information

Office Location: BESB 116
Email: hyunseok.hwang@tamuk.edu
Phone: 361-593-4170
CV: Download CV (PDF)

About Dr. Hwang

Dr. Hyun Seok Hwang is a cardiac electrophysiologist whose research focuses on sarcoplasmic reticulum (SR) calcium regulation under oxidative stress-induced cardiomyopathy. His work investigates molecular mechanisms of calcium handling, arrhythmogenesis, and the impact of oxidative stress on ion channel function and heart failure development. Through his teaching and research, Dr. Hwang trains students in physiology, integrative biology, and the molecular underpinnings of cardiovascular disease.

Education

• Ph.D., Kinesiology — University of Michigan, Ann Arbor
• M.A., Kinesiology — University of Texas at Austin
• B.S., Physical Education — Seoul National University, South Korea

Courses Taught

• BIOL 2401: Human Anatomy and Physiology I
• BIOL 3408: Animal Physiology

Research Interests & Current Projects

• Sarcoplasmic reticulum (SR) calcium regulation in cardiomyopathy
• Molecular mechanisms of calcium handling and arrhythmogenesis
• Impact of oxidative stress on ion channel function and heart failure

Selected Publications

• Hwang H, Kahmini AR, Prascak J, Carbonell AC, Valera IC, Champion S, Corrigan M, Mumbi F, Parvatiyar MS. (2023). Sarcospan deficiency increases oxidative stress and arrhythmias in hearts after acute ischemia-reperfusion injury. Int J Mol Sci, 24(14):11868.
• Landim-Vieira M, Ma W, Song T, Rastegarpouyani H, Gong H, Ottenheijm C, Hwang H, et al. (2023). Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function. Proc Natl Acad Sci USA, 120(23):e2221244120.
• Hwang H, Baldo M, Rodriguez J, Faggioni M, Knollmann B. (2019). Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia is Mutation-Independent but Reduced by Calcium Overload. Front Physiol, 10:992.
• Hwang H, Kryshtal D, Feaster TK, Sanchez-Freire V, Zhang J, Kamp TJ, Hong C, Wu JC, Knollmann B. (2015). Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories. J Mol Cell Cardiol, 85:79–88.
• Watanabe H, Chopra N, Laver D, Hwang H, et al. (2009). Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. Nat Med, 15(4):380–383.